According to the monoamine hypothesis, which statement is accurate?

The monoamine hypothesis suggests that mood disorders, particularly depression, may be linked to deficiencies in certain neurotransmitters, primarily serotonin, norepinephrine, and dopamine. Statement C, which indicates that abnormalities in various neurotransmitters cause depressive symptoms, aligns with this theory as it acknowledges the multifactorial nature of depressive disorders.

Research supports the idea that depression is not solely the result of a deficiency in one neurotransmitter but is rather influenced by the dysregulation of several neurotransmitter systems. This highlights the complexity of mood regulation and suggests that a combination of neurotransmitter imbalances contributes to the etiology of depression. Thus, addressing multiple neurotransmitter pathways can be crucial for effective treatment strategies.

The other statements either oversimplify the condition by attributing it to a single neurotransmitter or make claims about treatments that are not aligned with current understanding or empirical evidence regarding the efficacy of deep brain stimulation (DBS) in treating severe depression.